abstract：OPINION STATEMENT:To date, there are no approved and established pharmacologic treatment options for tauopathies, a very heterogenous group of neuropsychiatric diseases often leading to dementia and clinically diagnosed as atypical Parkinson syndromes. Among these so-called Parkinson plus syndromes are progressive supr...

journal_title：Current treatment options in neurology

authors： Karakaya T,Fußer F,Prvulovic D,Hampel H

更新日期：2012-04-01 00:00:00

abstract：:OPINION STATEMENT: Anemia develops in about 50% of patients hospitalized with traumatic brain injury (TBI) and is recognized as a cause of secondary brain injury. This review examines the effects of anemia and transfusion on TBI patients through a literature search to identify original research on anemia and transfusi...

journal_title：Current treatment options in neurology

authors： Kramer AH,Le Roux P

更新日期：2012-04-01 00:00:00

abstract：OPINION STATEMENT:Autoimmune neuromuscular disorders in childhood include Guillain-Barré syndrome and its variants, chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), juvenile myasthenia gravis (JMG), and juvenile dermatomyositis (JDM), along with other disorders rarely seen in childhood. In general, the...

journal_title：Current treatment options in neurology

authors： McMillan HJ,Darras BT,Kang PB

更新日期：2011-12-01 00:00:00

abstract：OPINION STATEMENT:When treating a person with epilepsy, one must consider many factors in addition to the obvious need to treat the seizures. Both epilepsy itself and treatment with antiepileptic drugs (AEDs) subject one to numerous potential secondary long-term health concerns. Poor bone health is one of these concern...

journal_title：Current treatment options in neurology

authors： Pack AM

更新日期：2011-08-01 00:00:00

abstract：OPINION STATEMENT:The management of herpes zoster (HZ) usually involves a multidisciplinary approach aiming to reduce complications and morbidity. Patients with herpes zoster ophthalmicus (HZO) are referred to ophthalmologists for prevention or treatment of its potential complications. Without prompt detection and trea...

journal_title：Current treatment options in neurology

authors： Sanjay S,Huang P,Lavanya R

更新日期：2011-02-01 00:00:00

abstract：OPINION STATEMENT:Pervasive developmental disorders (PDDs), including autistic disorder (autism), Asperger's disorder, and pervasive developmental disorder not otherwise specified (PDD NOS), are neurodevelopmental disorders of childhood onset. These disorders persist throughout the lifespan of affected individuals and ...

journal_title：Current treatment options in neurology

authors： Wink LK,Erickson CA,McDougle CJ

更新日期：2010-11-01 00:00:00

abstract：:After a patient has initiated an antiepileptic drug (AED) and achieved a sustained period of seizure freedom, the bias towards continuing therapy indefinitely can be substantial. Studies show that the rate of seizure recurrence after AED withdrawal is about two to three times the rate in patients who continue AEDs, bu...

journal_title：Current treatment options in neurology

authors： Hixson JD

更新日期：2010-09-01 00:00:00

abstract：OPINION STATEMENT:Triptans, selective serotonin receptor agonists, were developed almost 20 years ago and represented a major breakthrough in the treatment of acute migraine attacks. Since then, the triptans have become first-line agents for most patients with migraine, both with and without aura, unless contraindicate...

journal_title：Current treatment options in neurology

authors： Cole AK,Marmura MJ

更新日期：2010-09-01 00:00:00

abstract：OPINION STATEMENT:High-grade or malignant gliomas are aggressive cancers. The World Health Organization (WHO) grading system recognizes grade III and grade IV primary brain tumors of astrocytic, oligodendroglial, or mixed lineage. Identification of these tumors is prompted by symptoms such as insidious headaches, seizu...

journal_title：Current treatment options in neurology

authors： Giglio P,Villano JL

更新日期：2010-07-01 00:00:00

abstract：OPINION STATEMENT:The recognition of the diagnosis of migraine in the pediatric population is increasing. Early and aggressive treatment of migraine in children and adolescents with the use of over-the-counter medications has proven effective. In addition, the off-label use of many migraine-specific medications is ofte...

journal_title：Current treatment options in neurology

authors： O'Brien HL,Kabbouche MA,Hershey AD

更新日期：2010-05-01 00:00:00

abstract：OPINION STATEMENT:Melanoma-associated retinopathy is a rare paraneoplastic disorder that is challenging to diagnose and even more difficult to treat. Because of the rarity of the disease, therapy is based on analysis of case series and case reports. Based on evidence from these reports, first-line therapy is cytoreduct...

journal_title：Current treatment options in neurology

authors： Powell SF,Dudek AZ

更新日期：2010-01-01 00:00:00

abstract：:The treatments for obstructive sleep apnea (OSA) described in this paper represent the latest information and data. Nasal continuous positive airway pressure, initially described in 1981, remains the cornerstone of therapy. Advances in mask interfaces, the use of humidification, the downloading of usage information, t...

journal_title：Current treatment options in neurology

authors： Collop NA

更新日期：2009-09-01 00:00:00

abstract：:Medical management, the mainstay of treatment for partial epilepsy, involves choosing from an array of antiseizure drugs, most of which have comparable efficacy against partial-onset seizures. Effective treatment strategies involve matching the characteristics of drug and patient to control seizures without adverse ef...

journal_title：Current treatment options in neurology

authors： Liu L,Henry JC

更新日期：2009-07-01 00:00:00

abstract：:Drug-induced parkinsonism (DIP) is condition that mimics Parkinson's disease. Characterized mainly by rigidity and bradykinesia, it has less prominent tremor and gait instability. DIP is generally caused by lipophilic drugs that "block" dopamine D2 receptors in the brain, although presynaptic dopamine depletion, false...

journal_title：Current treatment options in neurology

authors： Susatia F,Fernandez HH

更新日期：2009-05-01 00:00:00

abstract：:Neuralgic amyotrophy has a broad variety of clinical manifestations. Although it was initially thought to be a plexopathy, its diverse presentation can include isolated sensory nerves or even cranial nerves. Although neuralgic amyotrophy is usually a benign condition with a good recovery, pain can be a disabling featu...

journal_title：Current treatment options in neurology

authors： Santana L,Gutierrez A

更新日期：2009-03-01 00:00:00

abstract：:Allodynia is a normal part of the untreated migraine attack in most people with episodic migraine and is prevalent in chronic migraine. The extent to which allo-dynia contributes to the pain and disability of migraine attacks is unclear, as is its clinical importance. The presence of allodynia correlates with the seve...

journal_title：Current treatment options in neurology

authors： Young WB

更新日期：2009-01-01 00:00:00

abstract：:Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by degeneration of spinal cord motor neurons and muscular atrophy. Advances in recent research have led to understanding of the molecular genetics of SMA. Therapeutic strategies have been developed according to the unique genomic structure o...

journal_title：Current treatment options in neurology

authors： Wang CH,Lunn MR

更新日期：2008-11-01 00:00:00

abstract：:There has been a recent resurgence of interest in therapeutic modalities using transcranial weak electrical stimulation through scalp electrodes, such as trans-cranial direct current stimulation (tDCS), as a means of experimentally modifying and studying brain function and possibly treating psychiatric conditions. A r...

journal_title：Current treatment options in neurology

authors： Bikson M,Bulow P,Stiller JW,Datta A,Battaglia F,Karnup SV,Postolache TT

更新日期：2008-09-01 00:00:00

abstract：:The elderly are the most rapidly growing segment of the population, and the incidence of epilepsy in persons over 65 is higher than in any other age group. In nursing homes, its incidence is even higher than in community-dwelling persons of similar ages. About 10% of nursing home residents are being treated with antie...

journal_title：Current treatment options in neurology

authors： Leppik IE

更新日期：2008-07-01 00:00:00

abstract：:Acute viral meningitis is the most common infection of the central nervous system. Most cases occur in children and young adults and are due to enteroviruses. Although the common causes of acute viral meningitis still lack treatment with an effective antiviral agent, management of patients is changing because of bette...

journal_title：Current treatment options in neurology

authors： Davis LE

更新日期：2008-05-01 00:00:00

abstract：:The mainstay of treatment of amyotrophic lateral sclerosis (ALS) is management of symptoms. Health care providers involved in the care of ALS patients should be armed with the most current knowledge about symptomatic management of these patients so that an aggressive approach to controlling symptoms can be undertaken ...

journal_title：Current treatment options in neurology

authors： Thibodeaux LS,Gutierrez A

更新日期：2008-03-01 00:00:00

abstract：:Neuromyelitis optica (NMO, Devic's syndrome) is characterized by concurrence of optic neuritis and transverse myelitis, typically associated with a lesion in the spinal cord extending over three or more vertebral segments. It is an inflammatory, demyelinating central nervous system disorder, and although it is most co...

journal_title：Current treatment options in neurology

authors： Wingerchuk DM,Weinshenker BG

更新日期：2008-01-01 00:00:00

abstract：:Sleep disorders can have a significant impact on the growth and development of children. Behavioral intervention is the first step in the management of many sleep disorders. Limit-setting is particularly challenging in younger children but must be consistent. Good sleep hygiene practices must be emphasized to adolesce...

journal_title：Current treatment options in neurology

authors： Lam JC,Mason TB

更新日期：2007-11-01 00:00:00

abstract：:Apathy is a common problem observed in numerous neurologic, psychiatric, and other medical conditions. It is independent from other symptoms and has been associated with a variety of negative outcomes. However, little empirical research has been conducted on potential psychologic or pharmacologic treatments for apathy...

journal_title：Current treatment options in neurology

authors： Roth RM,Flashman LA,McAllister TW

更新日期：2007-09-01 00:00:00

abstract：:Transplantation of bone marrow or peripheral blood stem cells is increasingly being used to treat a variety of oncologic disorders. These procedures are associated with a large spectrum of neurologic complications that significantly contribute to patient morbidity and mortality. These complications may arise at any ti...

journal_title：Current treatment options in neurology

authors： Mathew RM,Rosenfeld MR

更新日期：2007-07-01 00:00:00

abstract：:Dystonia is a neurologic disorder that can occur at any age and often results in significant disability. The therapeutic application of botulinum toxin has revolutionized the treatment of this disorder, particularly for the adult-onset focal forms such as cervical dystonia and blepharospasm. The two available commerci...

journal_title：Current treatment options in neurology

authors： Cardona-Garcia OD,Higgins DS,Molho ES

更新日期：2007-05-01 00:00:00

abstract：:Although estimates vary, the nervous system appears to be involved in 10% to 15% of patients infected with Borrelia burgdorferi. The resulting disorders, known collectively as neuroborreliosis or nervous system Lyme disease, generally respond well to antimicrobial therapy. Definitive treatment of nervous system infect...

journal_title：Current treatment options in neurology

authors： Halperin JJ

更新日期：2007-03-01 00:00:00

abstract：:Cervicocranial arterial dissection (CCAD) occurs when there is a tear in the intimal layer of the carotid or vertebral arteries with subsequent extravasation of blood into the subintimal layers. The dissection may be extradural, intradural, or extend over both segments. The contents of the subintimal layers are highly...

journal_title：Current treatment options in neurology

authors： Shah Q,Messé SR

更新日期：2007-01-01 00:00:00

abstract：:The epidemiologic link between increased low-density-lipoprotein (LDL) cholesterol and ischemic stroke is controversial. However, recent trials make it clear that LDL reduction by statin agents in high-risk patients reduces the risk of ischemic stroke. The risk of first stroke is reduced within 1 to 2 years of statin ...

journal_title：Current treatment options in neurology

authors： Bernstein RA

更新日期：2006-11-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease that usually results in death secondary to respiratory failure. The psychological reaction to the diagnosis of ALS in patient and caregiver has received increasing attention. Reports are highly variable as to the severity of depressive symptoms ...

journal_title：Current treatment options in neurology

authors： Stromberg SF,Weiss DB

更新日期：2006-09-01 00:00:00

abstract：:A sleep history should be taken routinely in patients with epilepsy. Treatment of sleep disorders and improvement in sleep hygiene may improve seizure control, daytime cognitive functioning, and quality of life. Patients with recurrent sleepiness interfering with daily activities or an Epworth Sleepiness Scale score m...

journal_title：Current treatment options in neurology

authors： Herman ST

更新日期：2006-07-01 00:00:00

abstract：:Progressive supranuclear palsy (PSP) is an atypical parkinsonian disorder that, in spite of its growing recognition, is still underdiagnosed. For management, prognosis, and research, an accurate and early diagnosis is essential. PSP is a relentlessly progressive neurodegenerative disorder, clinically characterized by ...

journal_title：Current treatment options in neurology

authors： van Balken I,Litvan I

更新日期：2006-05-01 00:00:00

abstract：:Spontaneous intracerebral hemorrhage (ICH) is a devastating neurological event with a 30-day mortality of approximately 40%. Recent research provides new insights into the pathophysiology of ICH-associated edema, with potential molecular and cellular targets for future therapy. Neuroimaging techniques such as gradient...

journal_title：Current treatment options in neurology

authors： Freeman WD,Brott TG

更新日期：2006-03-01 00:00:00

abstract：:Patients with functional or nonorganic visual disturbances are often seen in general ophthalmology practice and then referred to neurology and/or neuro-ophthalmology. The diagnosis of functional vision loss requires comprehensive examinations and diagnostic testing to eliminate possible organic entities. Inconsistenci...

journal_title：Current treatment options in neurology

authors： Leavitt JA

更新日期：2006-01-01 00:00:00

abstract：:Cerebrovascular disorders are an important cause of mortality and chronic morbidity in children. Ischemic stroke is more common than cerebral venous thrombosis and hemorrhagic stroke in children. Several medical disorders have been associated with stroke in children, and a thorough evaluation of underlying causes is n...

journal_title：Current treatment options in neurology

authors： Lynch JK,Pavlakis S,Deveber G

更新日期：2005-11-01 00:00:00

abstract：:Despite increasing recognition of childhood obstructive sleep apnea syndrome (OSAS) as a significant public health problem, treatment of the condition remains inconsistent. Some children are screened using polysomnography and treated only when objective respiratory disturbances are identified. Many others receive aden...

journal_title：Current treatment options in neurology

authors： Hoban TF

更新日期：2005-09-01 00:00:00

abstract：:Antiepileptic drug (AED) treatment is associated with multiple short- and long-term side effects. Effects on endocrine function, including weight change, reproductive function, thyroid function, and bone health are examples of these side effects. Some AEDs affect weight, resulting in weight gain or loss. Levetiracetam...

journal_title：Current treatment options in neurology

authors： Pack A

更新日期：2005-07-01 00:00:00

abstract：:Neuromyelitis optica (Devic's syndrome) is an uncommon, idiopathic, demyelinating syndrome of the central nervous system that preferentially affects the optic nerves and spinal cord. It frequently is misdiagnosed as severe multiple sclerosis, but usually is readily distinguished from multiple sclerosis in fully develo...

journal_title：Current treatment options in neurology

authors： Wingerchuk DM,Weinshenker BG

更新日期：2005-05-01 00:00:00

abstract：:The challenge for the neurologist in the treatment of Lyme neuroborreliosis is not in the treatment per se, but in the diagnosis. Neurological manifestations of Lyme disease can present in many forms, and diagnostic techniques which detect the spirochete directly; the culture or polymerase chain reaction of the spiroc...

journal_title：Current treatment options in neurology

authors： Pachner AR

更新日期：2005-03-01 00:00:00

abstract：:Myasthenia gravis (MG) is an autoimmune disorder characterized clinically by proximal weakness and bulbar symptoms and pathologically by damage to the post-synaptic membrane at the neuromuscular junction. Ocular myasthenia gravis (ocular MG) is a form of myasthenia gravis whereby the patients' weakness is limited to t...

journal_title：Current treatment options in neurology

authors： Porter NC,Salter BC

更新日期：2005-01-01 00:00:00